Albenza Drug Uses

Albenza is indicated for the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm. This medicine may also be used for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm.

How Taken

Albenza should be taken with food.

Albenza Warnings/Precautions

Albenza may cause fetal harm, therefore, you should begin treatment after a negative pregnancy test. During therapy, because of the possibility of harm to the liver or bone marrow, routine (every 2 weeks) monitoring of blood counts and liver function tests should take place. Talk to your doctor about possible harm to the fetus if you plan on becoming pregnant while on Albenza or within 1 month of completing treatment.

Albenza Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Albenza Possible Side Effects

The symptoms are usually mild and resolved without treatment.

Albenza Storage

Store between 20° and 25°C (68° and 77°F).

Albenza Overdose

In case of overdosage, symptomatic therapy and general supportive measures are recommended. Seek emergency medical attention.

More Information

If you suffer of hypersensitivity to the benzimidazole class of compounds or any components of Albenza, talk to your doctor before taking this medicine.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Most people have no recognized symptoms. The immune system usually keeps the parasite from causing acute illness. If the infection is acquired for the first time while a woman is pregnant, however, it can cause serious problems for the fetus, including severe eye and brain damage.
The National Collaborative Chicago-Based Congenital Toxoplasmosis Study followed 120 infants from the United States and Canada who had been diagnosed with toxoplasmosis soon after birth and were referred, between 1981 and 2004, for treatment and periodic evaluation by the study team. Eighty percent of these infants (96/120) had clinical abnormalities at birth, often severe.
Patients were treated with pyrimethamine at one of two different dose levels and sulfadiazine for one year and then followed periodically. Follow-up evaluations assessed neurologic status, including movement abnormalities and cognitive function, vision, including the development of new lesions in the eye, and hearing loss.
The authors emphasize that the median age of these children is about 10 years and longer follow up into adulthood is needed to determine whether these current favorable outcomes are sustained.
Almost all of the outcomes were markedly better than the previously reported outcomes for children who were either untreated or treated for only one month, which was the usual approach at the beginning of the study.
Of the 96 children in this study who had severe disease at birth, 47 have been in the study for at least 7.5 years. Eighty percent of the children with severe disease now have normal motor function; 73 percent have IQs greater than 70; 84 percent have had no decrease in IQ of 15 points between evaluations. (Such a decrease is a sign of a progressing infection.)
Although most of these patients had eye disease at the beginning of the study and 85 percent have some impairment of vision, 64 percent have had no new retinal lesions since beginning treatment.
Unfortunately 11 of the 96 severely affected infants died, nine of them from respiratory infections associated with their disability. None of the deaths were related to treatment.
Of the 24 children who had no, mild or moderate symptoms at birth, 11 have already reached the age of 7.5 years. All 24 have normal motor and cognitive function and hearing. One child older than 7.5 years had a 15-point IQ decrease between evaluations. One developed a new retinal lesion.
‘The majority of the children in our cohort are entering adolescence without experiencing recurrent eye lesions or seizures and with normal cognitive and motor function,’ the authors wrote. This congenital infection, they added, is ‘preventable and treatable.’
‘Prior studies had shown that untreated children or children who received a short course of therapy (1 month) did poorly,’ noted Kami Kim, M.D., professor of infectious diseases and medicine at Albert Einstein College of Medicine, in a commentary in the journal. In this present study, ‘children with severe disease had a remarkably better outcome.’
This promising result provides ‘compelling evidence’ for prolonged treatment, she said. Because such treatment improves outcome, ‘it may be time to consider a more comprehensive plan for neonatal screening for congenital toxoplasmosis.’
More than one year ago, the research team recommended systematic toxoplasmosis screening for all pregnant women in the United States during prenatal visits, as well as screening for congenital toxoplasmosis in all newborns.
Most states already require screening of newborns for a number of genetic and metabolic diseases that are less common than toxoplasmosis, but there is no systematic program for screening for toxoplasmosis during pregnancy in the United States. The Genetics Newborn Screening Advisory Group noted that the rationale for screening for toxoplasmosis was as compelling as the rationale for detection of genetic diseases for which screening is now mandated in many states.

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